Lypo-Spheric^™ Vitamin C delivers so much more vitamin C you'll KNOW it's working — guaranteed!

Lypo-Spheric™ Vitamin C is the first choice of people who really understand bioavailability and the importance of high-dose vitamin C. Right out of the gate all other forms of vitamin C rapidly crash into an absorption barrier that vastly limits the level of vitamin C that can enter the bloodstream... and the vitamin C that doesn't get absorbed, gets flushed. (Important note: all the vitamin C in your food is just as restricted by this absorption barrier.)

In stark contrast, the "Smart" Lyposomal Nano-spheres® that encapsulate Lypo-Spheric™ Vitamin C gently slip across the intestinal wall and into the blood. That's because they are able to completely bypass a very restrictive nutrient transport system that radically limits the bioavailability of all non-liposome encapsulated forms of vitamin C. A recent clinical trial by world-renowned vitamin C expert and pharmacologist, Steve Hickey, PhD, shows that Lypo-Spheric™ Vitamin C is able to produce serum levels of vitamin C nearly double those thought theoretically possible with any oral form of vitamin C. This astounding level of bioavailability not only dramatically increases the amount of vitamin C in the blood, but recent thermographic microscopy provides visible evidence that it also aids its entry into individual cells.

Try it and you'll see and feel superior delivery and enhanced results for yourself — guaranteed! 

Squeeze the contents of one packet into your favorite juice or other cool beverage. It's easy to swallow. Within minutes millions of "Smart" Lyposomal Nano-Spheres® loaded with vitamin C will move into your bloodstream and then into your cells. Once there, the "essential" phospholipids and the vitamin C will be unleashed to perform their powerful work!

Each 0.2 oz. packet of Lypo-Spheric™ Vitamin C contains 1,000 mg of vitamin C and 1,000 mg of "essential" phospholipids. It's the most bio-available, easy-to-swallow vitamin C supplement on the market.

Lypo-Spheric Vitamin C - Numerous Positive Effects:

• Lypo-Spheric Vitamin C is a powerful Antioxidant with extraordinary benefits

• Provide rapid and positive impact on CARDIOVASCULAR FUNCTION (C.V.)

• Help to prevent impaired liver function linked to excessive fatigue, accelerated aging, weight problems, impaired immunity.

• Increase metabolism, endurance, energy and stamina.

• Help the body form the protein COLLAGEN that builds bone structure, cartilage and blood vessels.

• Help to decrease cholesterol and lead toxicity.

• Help to IMPROVE MEMORY.

• Help to INCREASE LONGEVITY and overall immune system.

What Experts Are Saying...

“Comparing the bioavailability of all other oral vitamin C delivery with your oral liposomal delivery is like comparing a squirt gun to a fire hose. Not only am I convinced that the efficacy of Lypo-Spheric™ Vitamin C far surpasses any traditional oral vitamin C supplement, but my recent personal experience with it suggests that it may sometimes be better than IV injection.” Thomas E. Levy, MD, JD  Author of Primal Panacea

"The hot new neutraceutical on the block - LivOn's Lypo-Spheric Vitamin C - is almost as good as a C drip..." Read more...

“Love your liposomal vitamin C product. For many people, my brother included, who cannot tolerate sufficient ordinary vitamin C, it is a lifesaver.” Owen Foronow - President, Vitamin C Foundation

“Your liposomal vitamin C takes full advantage of the amazing benefits of liposome encapsulation technology. Great product!” Robert D. Milne, MD Author of PC Liposomal Encapsulation Technology

The importance of bioavailability

This chart represents one of the more optimistic views of vitamin C bioavailability. A National Institutes of Health study suggests that only 200 mg of a single dose, regardless of size, actually gets into the bloodstream. Bioavailability, is only half of the picture, however. The nutrient must also be able to pass into individual cells.

Until a nutrient actually passes from the digestive system into the bloodstream, it has little or no value. Although bioavailability is only a partial measure of the body’s ability to benefit from a nutrient, this number quantifies the amount of a substance that successfully enters the bloodstream. Once in the bloodstream, the nutrient must cross cellular membranes before it can nourish hungry cells.

When all of a nutrient is absorbed into the bloodstream, as in a direct intravenous injection, the bioavailability is 100%. If only a quarter of an ingested nutrient is absorbed, the bioavailability is 25%. Of course, bioavailability also depends on and is limited by other factors such as declining health status, advancing age, and the presence of other substances that compete for absorption.

The process of uptake from the digestive system varies greatly from nutrient to nutrient. Vitamin C is absorbed almost exclusively in the small intestine and requires the presence of transport proteins. For vitamin C, these transport proteins are called sodium-dependent vitamin C co-transporters (SVCTs). A lack of these proteins produces a corresponding lack of vitamin C uptake. Published research confirms that SVCTs (transport proteins) tightly regulate vitamin C bioavailability.

In one study with non-liposome-encapsulated vitamin C, 19 mg of a 20 mg oral dose entered the bloodstream — a bioavailability of 98%. As the dose size increased beyond 30 mg, the bioavailability decreased drastically. They reported that a dose of 12,000 mg produced a maximum bioavailability of 16%!

A study by the National Institutes of Health reveals an even more restrictive control of non-liposome-encapsulated vitamin C uptake. It found that a maximum of 200 mg of non-liposome-encapsulated vitamin C is bioavailable at any given time. What happens to all non-absorbed vitamin C? It moves into the colon where it is excreted. For some individuals, an excess of vitamin C in the colon causes several unpleasant symptoms including cramps and diarrhea.

Cellular uptake is required to obtain maximum benefit from nutrients. Recent fluorescent microscopy from laboratory tests with LivOn's "Smart" Lyposomal Nano-Spheres®, confirms passage of these liposomes across cellular membranes and into cultured liver cells. The bright magenta spots show that uptake of fluorescent-dye-tagged liposomes.

Once vitamin C enters the bloodstream, an active transport process is needed for the nutrient to move across any cellular membrane. This process can be just as restrictive as the one that initially limited the nutrient's entrance into the bloodstream. Much of the vitamin C that is not actively transported into the cells will be filtered out by the kidneys and passed in the urine.

Liposome encapsulation overcomes all these bioavailability and cellular uptake restrictions because liposomes do not rely on SVCTs or any other carrier transport system. Instead, due to their size and composition, they are able to passively absorb through the intestinal wall and through cellular membranes. As a result, liposome-encapsulated nutrients (like Lypo-Spheric™ Vitamin C) provide a greatly enhanced bioavailability (delivery into the bloodstream) and greatly improved delivery into individual cells.

So what are liposomes, exactly?

Representation of a phospholipid molecule showing phosphate head (orange), the glycerol sholders (blue) and the fatty acid tails (silver)

Liposomes are bilayer (double-layer), liquid-filled bubbles made from phospholipids. Over 50 years ago, researchers discovered that these spheres could be filled with therapeutic agents and used to protect and deliver these agents into the body and even into specific cells of the body.

The bilayer structure of liposomes is nearly identical to the bilayer construction of the cell membranes that surround each of the cells in the human body. This occurs because of the unique composition of phospholipids. The phosphate (source of "phospho" in phospholipid) head of phospholipids is hydrophilic — it loves water — whereas the fatty-acid tails (lipids) are hydrophobic — they hate water.

Liposome containing vitamin C. Currently liposome-encapsulation is the best oral way to deliver vitamin C known to man.

When phospholipids find themselves in a water-based solution, the hydrophobic tails quickly move to distance themselves from the liquid just like oil separates from vinegar. So, as all the tails turn inward and all the heads turn toward the liquid, they form a double-layered membrane with all the tails pointing toward one another and the heads facing the outside or the inside of the sphere that they have formed.

This diagram of a liposome cutaway shows how the tails of phospholipids turn inward to form a bilayer membrane, and in so doing encapsulate a therapeutic agent.

Although research has not clearly shown how the therapeutic agents in a liposome are actually released, there are a couple of theories. One theory suggests that the phospholipids are processed in the liver as fats and that this process releases the vitamin C. Another theory proposes that cells all over the body, hungry for phospholipid materials to repair cell membranes and other cellular structures, "steal" these materials from the liposome allowing their contents to leak out.

Quite possibly both processes occur. In any case, the therapeutic value and greatly increased delivery of liposome-encapsulated drugs and nutrients has been scientifically confirmed countless times. At present, liposomes are the most effective oral way to deliver nutrients.

Essential phospholipids: what are they?

Phosholipids align themselves in a tail-to-tail formation with their heads facing outward which creates a double layer membrane. This bilayer structure is used by cells throughout the body for outer membranes as well as for structures inside each cell.

Phospholipids are the primary building blocks of cellular membranes. These membranes are the "containers" that hold the living matter within each cell. They also give definition, shape, and protection to many of the substructures (organelles within the cell like the nucleus and mitochondria) within our cells.

In addition to functioning as a skin for each cell — keeping the insides in and the outsides out — phospholipid membranes provide protection from chemicals and pathogens that can derail and/or destroy the necessary life functions that take place within each cell. While performing this function, phospholipid membranes are subject to constant attack from free radicals (oxidants), pathogens, and toxins.

In order to repair the structural damage caused by the continual barrage of toxic substances and pathogens, your body requires a constant supply of phospholipids. The body can synthesize some phospholipid compounds but others must be supplied by the diet. Phospholipids that can only be obtained through dietary intake are called "essential phospholipids."

Anatomy of a phosphatidylcholine molecule. All phospholipids have a phosphate group and fatty acid chains connected by a glycerol group. Phosphatidylcholine, a class of essential phospholipids, has two distinguishing characteristics: 1) a choline head and 2) one of the fatty acid chains is an omega-6 fatty acid. (KEY — Gray: carbon atoms; Teal: hydrogen atoms; Blue: oxygen atoms; Violet: phosphorus atom; Gold: nitrogen atom.)

At the basic level, phospholipids are a phosphate group (phospho) attached to fatty acids (lipids) by means of a glycerol group.

Unlike phosphates, which are attracted to water (hydrophilic), fatty acids are repelled by water (hydrophobic). It is this very love/hate relationship with water that allows phospholipids to form cellular membranes — and liposomes as well.

As phospholipids are exposed to water-based solutions, they automatically align themselves in a double-layer (bilayer) configuration — phosphates toward the water and fatty acids away from the water.

One of the most important and prominent phospholipids in cell membranes is called phosphatidylcholine (PC) [pronounced FOSS-fah-tide-al-KOH-lean]. At birth up to 90% of cellular membranes are made up of PC. As humans age, the percentage of PC in their cellular membranes can decrease to about 10%. This fact leads many to recommend consistent supplementation with this essential phospholipid.

Intact PC — as well as its essential fatty acid and choline components — is required for many vital functions in the cardiovascular, reproductive, immune, and nervous systems. PC and its components are needed for the synthesis of important messenger molecules called prostaglandins which, among other functions, regulate the contraction and relaxation of muscles. Choline is required for the synthesis of intracellular messenger molecules including the neurotransmitters that allow nerve cells to communicate with muscles and each other, and are essential for proper heart and brain function.

The liposomes used for Lypo-Spheric™ Vitamin C, AGE Blocker™, and Lypo-Spheric™ GSH are made from essential phospholipids including a rich blend of phosphatidylcholine. These liposomes not only provide optimum protection and superior transport for these supplements, they also help satisfy the body's need for PC, omega-6 fatty acids, and choline.

Frequently Asked Questions

Lypo-Spheric^™ Vitamin C

Q: Why do the Lypo-Spheric™ Vitamin C packets get puffy?

A: During the packaging process, carbon dioxide (CO2) is used to remove excess oxygen from the packets. Over time carbon dioxide can cause the packets to swell. This gas is not harmful to the liposomes and poses no health risk as your body makes and expels large amounts of it every day.

Q: Why is there alcohol in the Lypo-Spheric™ Vitamin C?

A: There is alcohol in the product for preservative purposes. This is a pharmaceutical grade natural grain alcohol which will not cause any ill effects in the body. In fact, your body makes more alcohol while digesting a regular meal than is in the product. If you do not wish to consume the alcohol in the product, open the packet and let it sit for 10-15 minutes to let the alcohol evaporate. (Do not let it sit for more than 4 hours because it will oxidize).

Q: Last time I purchased the Lypo-Spheric™ Vitamin C, the contents were a different color. Did you change the formula?

A: The formula has not changed, but the difference in color is completely normal. The vitamin C can range from a light honey color to a dark amber brown color. This is due to the variation in the color of the phospholipids used to encapsulate the vitamin C.

Q: Will supplementing with vitamin C lead to the development of kidney stones?

A: Although some have theorized a correlation between vitamin C and the development of kidney stones, overwhelming evidence contradicts this hypothesis. Broad population studies suggest that those with the highest blood levels of vitamin C have the lowest incidence of kidney stones.

FOR MORE INFO PLEASE VISIT   http://www.livonlabs.com/cgi-bin/htmlos.cgi/1978.5.049947836914741721/liposome-encapsulated/index.html